Preheat your oven to 375 degrees Fahrenheit and grease a 9-inch pie pan or cake pan. This ensures your rolls don’t stick during baking, making cleanup easier.
In a large mixing bowl, stir together the Bisquick mix, granulated sugar, and buttermilk just until a dough forms. It’s okay if there’s a little dry Bisquick remaining; you can add a splash more buttermilk if needed. The dough should be soft but not too sticky.
Sprinkle some flour on a clean surface – you can use a pastry mat, counter, or even parchment paper. This will help you roll out the dough without it sticking.
Roll the dough out into an approximate rectangle of 8 by 12 inches. Aim for an even thickness so that the rolls bake uniformly. You want it to be about half an inch thick.
In a small bowl, combine the brown sugar and ground cinnamon. Then, add 2 tablespoons of the melted butter and mix it in to create a paste-like filling.
Brush the remaining melted butter over the rolled-out dough. This adds flavor and helps the cinnamon mixture stick.
Evenly sprinkle the cinnamon mixture over the entire surface of the dough. Make sure to cover every inch to ensure every bite is flavorful.
Now, roll the dough up jellyroll style, starting at one of the long ends. Keep the roll tight but not so tight that the filling spills out.
Use dental floss or a sharp knife to slice the rolled dough into 8 equal pieces. These will be your individual rolls. Dental floss can help make clean cuts without squishing the rolls.
Place the rolls in your prepared pan. Make sure they’re snug but not overcrowded, as they will expand while baking. Bake in the preheated oven for about 22 to 25 minutes, or until the centers are no longer gooey. You want them golden brown.
While the rolls bake, prepare the glaze. In a medium bowl, whisk together the powdered sugar, melted butter, heavy cream, and vanilla extract until smooth. If it’s too thick, add a bit more heavy cream until you reach your desired consistency.
Once the rolls are done, let them cool for a few minutes before drizzling the glaze over the top. Enjoy your delicious Bisquick Cinnamon Rolls warm from the oven!