John Wayne Casserole
Growing up, comfort food was a cornerstone of family gatherings, and one dish that always stood out was the John Wayne Casserole. I remember the warm, inviting aroma wafting through the house as it baked to perfection, making it nearly impossible to resist sneaking a taste before dinner. This casserole isn’t just a meal; it’s a memory, a blend of flavors that brings my family together. Every bite of this hearty dish reminds me of those cozy evenings spent around the dinner table, sharing stories and laughter. With layers of deliciousness, the John Wayne Casserole has become a go-to recipe for any occasion, whether it’s a casual family dinner or a festive gathering. It’s truly a crowd-pleaser that never fails to impress.
Recipe Snapshot
50 mins
10 mins
40 mins
Medium
480 kcal
25 g
Gluten-Free, Low FODMAP
30 g
9×13 casserole dish, Skillet
What Sets This John Wayne Casserole Apart
Comfort in Every Bite
The John Wayne Casserole stands out as a comforting dish that warms both body and soul. It’s that satisfying combination of flavors and textures that keeps you coming back for more. The crispy biscuit base, savory ground beef, and a medley of veggies create a delightful contrast that’s hard to resist.
Easy to Prepare
This casserole is incredibly simple to throw together, making it perfect for busy weeknights. With just a few ingredients and minimal prep time, you’ll have a delicious meal ready in no time. I love how it can be assembled ahead of time and baked just before serving, making it a great option for entertaining.
Versatile Ingredients
The beauty of the John Wayne Casserole is in its versatility. You can easily adapt the ingredients to suit your preferences or what you have on hand. Feel free to swap out the veggies or even the protein, making it a flexible staple that can be enjoyed in many different ways.
Great for Feeding a Crowd
This dish is perfect for gatherings or potlucks. With its generous servings, the John Wayne Casserole ensures that everyone gets a hearty portion. Plus, it satisfies even the pickiest eaters, making it a safe bet for any group meal.
Leftovers Never Go to Waste
One of my favorite things about the John Wayne Casserole is that it makes for fantastic leftovers. The flavors meld beautifully overnight, making the next day’s meal just as delightful as the first. You can easily reheat it for lunch or dinner, ensuring nothing goes to waste.
Perfect for Any Season
Whether it’s a chilly fall evening or a summer family BBQ, the John Wayne Casserole is suitable for any occasion. It’s comforting enough to be a staple in the colder months while still being light and enjoyable during warmer weather.
Ingredients You’ll Need for John Wayne Casserole

The ingredients for the John Wayne Casserole come together beautifully to create a satisfying meal. Each component plays a vital role in contributing flavor and texture, making this dish a well-rounded option for any table. Let’s dive into the key players that make this casserole a family favorite.
- 1 16-ounce can refrigerated large biscuits – These form the buttery base, providing a soft and flaky foundation.
- 2 tablespoons olive oil – Essential for cooking the beef and sautéing the vegetables.
- 2 pounds ground beef – The primary protein source, bringing a hearty flavor to the dish.
- 3 tablespoons taco seasoning – Adds a zesty kick, infusing the beef with rich flavors.
- ½ teaspoon salt – Enhances the overall taste; add only if your seasoning is salt-free.
- ¼ cup water – Helps to keep the meat mixture moist during cooking.
- 1 14-ounce can ROTEL diced tomatoes & green chilies – Introduces a tangy and spicy element.
- 1 14-ounce can canned corn – Adds sweetness and texture; you can substitute with fresh or frozen corn.
- 1 medium yellow onion – Provides a savory base flavor when sautéed.
- 1 medium red bell pepper – Offers a pop of color and sweetness to the casserole.
- ½ cup mayonnaise – Creamy topping that binds the flavors together.
- ½ cup sour cream – Adds tanginess and richness to the topping.
- 1 tablespoon onion powder – Enhances the onion flavor without overpowering the dish.
- 1 cup shredded mild cheddar cheese – Melts beautifully, providing creaminess and flavor.
- 1 cup shredded mozzarella cheese – Adds stretchiness and a mild flavor to the topping.
- Chopped fresh parsley – A garnish that adds freshness and color.
Putting Together John Wayne Casserole

Making the John Wayne Casserole is a straightforward process that anyone can tackle. It’s about layering flavors and textures to create a dish that will impress. Follow these detailed steps to achieve the perfect casserole.
Preheat your oven to 350°F/180°C, and prepare a 9×13 inch casserole dish by spraying it with non-stick cooking spray. This step is crucial to ensure the biscuits don’t stick to the dish.
Open the can of refrigerated biscuits and press them into the bottom of the prepared dish. Make sure they overlap slightly to cover the entire surface. Bake the biscuits in the preheated oven for about 15 minutes until they are lightly golden. This will serve as the crispy base of your John Wayne Casserole.
While the biscuits are baking, take a skillet and heat 1 tablespoon of olive oil over medium heat. Add the ground beef and cook it, breaking it up with a spatula until it’s browned. This should take about 5 to 7 minutes. Drain any excess fat to keep the dish from being greasy.
Once the beef is browned, sprinkle in the taco seasoning and stir to combine. If needed, add a pinch of salt and pour in the water. Continue cooking for another 3 to 4 minutes until everything is well combined and heated through.
Next, add the ROTEL tomatoes and corn to the skillet. Stir gently and cook for just a few minutes until the mixture is warmed through. This vibrant mix adds a burst of flavor and color to your casserole.
Remove the skillet from the heat and pour the beef mixture over the baked biscuit base in the casserole dish. Spread it evenly with a spatula, ensuring every bit of the biscuit is covered.
Now, wipe the skillet clean with a paper towel and return it to the stovetop. Heat the remaining tablespoon of olive oil, and add the onion and red bell pepper. Sauté them for about 2 minutes until they are cooked but still slightly firm. This adds a lovely crunch to the casserole.
Layer the sautéed vegetables over the beef in the casserole dish, distributing them evenly across the surface. The combination of flavors will be delightful!
In a separate bowl, mix together the mayonnaise, sour cream, onion powder, and half of both the cheddar cheese and mozzarella cheese. This creamy topping will take your casserole to the next level.
Spread the creamy mixture over the layered vegetables, then sprinkle the remaining cheese on top. Pop the casserole back into the oven and bake for 20 to 30 minutes until the cheese is melted and bubbly, and the top is starting to brown.
Once baked, remove the casserole from the oven and let it cool for a few minutes. Garnish with chopped parsley before serving, adding a fresh touch to your delicious meal.
Things Worth Knowing
- Make sure to preheat the oven properly to ensure even baking.
- For a crispier biscuit layer, bake the biscuits for a few extra minutes before adding the filling.
- If you like a little heat, choose spicy ROTEL for a kick.
- You can customize the vegetables based on what’s in season or what you have on hand.
Recipe Tips about John Wayne Casserole

When it comes to perfecting your John Wayne Casserole, there are a few tips that can make a big difference. Here are some insights to enhance your experience:
- Storage: Store leftover casserole in an airtight container in the fridge. It will stay fresh for 3 to 4 days and can be easily reheated in the microwave or oven.
- Freezing: Transfer leftovers to a freezer container and store in the freezer for up to 3 months. Defrost overnight in the refrigerator before reheating.
- Pairing: Serve with a fresh salad or garlic bread to complement the casserole’s rich flavors.
- Variety: Feel free to mix in different veggies or beans to create variations of this dish.
- Cheese Options: Experiment with different cheese blends, like pepper jack or Monterey Jack, for varied flavors.
- Spice Level: Adjust the spice level by choosing different taco seasoning or adding diced jalapeños.
Great Combinations for John Wayne Casserole
When serving the John Wayne Casserole, there are plenty of delicious options to consider. Here are some great combinations:
- Side Salads: Pair this hearty casserole with a crisp garden salad or a Caesar salad for a refreshing contrast.
- Garlic Bread: Serve with warm garlic bread for a comforting side that complements the flavors of the casserole.
- Occasions: This dish is perfect for family gatherings, potlucks, or a cozy dinner at home.
- Seasonal Pairings: In the fall, consider serving with apple cider or pumpkin-flavored desserts for a seasonal touch.
- Leftover Magic: Use leftovers to make stuffed bell peppers or tacos the next day!
- Meal Prep: Assemble the casserole ahead of time and bake it just before serving for a hassle-free meal.
FAQ
Conclusion
The John Wayne Casserole is a warm, satisfying dish that brings comfort to any table. Its rich flavors and hearty ingredients make it a perfect choice for family dinners or gatherings. I encourage you to try making this casserole—it’s sure to become a favorite in your home, just like it is in mine!

John Wayne Casserole
Ingredients
Equipment
Method
- Preheat the oven to 350°F/180°C, and spray a 9×13 inch casserole dish with non stick cooking spray.
- Press the biscuits into the bottom of pan so they overlap and cover the entire surface. Bake for 15 minutes.
- In a skillet, heat 1 tablespoon of olive oil and cook and crumble the ground beef until browned. Drain away the fat, then season with taco seasoning. Add salt if needed, then add water and cook for 3-4 minutes, stirring to combine.
- Add the ROTEL tomatoes and the corn to the meat and cook until the mixture is just warmed through, then pour the meat over the cooked biscuit layer.
- Wipe the skillet clean, heat the remaining oil and saute the onion and peppers for about 2 minutes until they are cooked but still firm. Season with a pinch of salt. Layer the vegetables over the ground beef in the casserole dish.
- To make the topping, combine the mayonnaise, sour cream, onion powder and half of both the cheddar and mozzarella cheeses in a bowl. Layer this over the vegetables, then sprinkle the remaining cheeses on top.
- Bake for 20-30 minutes, or until the cheeses are melted and starting to brown. Remove from the oven, and garnish with fresh parsley before serving.


